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    <journal-meta>
      <journal-id journal-id-type="publisher-id">journal-of-clinical-obstetrics-and-gynecology-research</journal-id>
      <journal-title-group>
        <journal-title>Journal of Clinical Obstetrics and Gynecology Research</journal-title>
      </journal-title-group>
      <issn publication-format="electronic">2766-2756</issn>
      <publisher>
        <publisher-name>Directive Publications</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-categories><subj-group subj-group-type="heading"><subject>Research</subject></subj-group></article-categories>
      <title-group>
        <article-title>In normal and growth-restricted pregnancies, doppler velocimetry of the cerebral and middle cerebral arteries was performed</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Obstetrics</surname>
            <given-names>Clinical</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>In</surname>
            <given-names>Gynecology Research</given-names>
          </name>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub">
        <day>19</day>
        <month>06</month>
        <year>2026</year>
      </pub-date>
      <permissions>
        <copyright-statement>© 2026 The Author(s). Published by Directive Publications.</copyright-statement>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0).</license-p>
        </license>
      </permissions>
      <abstract>
        <p>To concentrate on the results like occurrence of Cesarean conveyance, birth weight, apgar score and rate of admis- sion to NICU among the review bunch and the benchmark group. To concentrate on connection of Cerebro-umbilical proportion with the results and to lay out meaning of Dop- pler files. Planned observational concentrate in a tertiary consideration medical clinic. Complete of 120 patients were considered, 60 in concentrate on gathering and 60 in control bunch. Doppler boundaries were concentrated on in both the gatherings utilizing Chi square test, Kruskall Wallis test and Fisher’s careful test. The rate of instigated work, Cesarean conveyance, apgar score being low at 1 moment and NICU affirmations were nearly higher in the review bunch when contrasted with con- trol bunch. S/D proportion of the Umbilical course showed measurable importance to foresee the results referenced. Key words Apgar score, cerebroumbilical ratio, and pulsatility index.</p>
      </abstract>
    </article-meta>
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      <p>Introduction Fetal monitoring during pregnancy is essential to lowering perinatal morbidity and mortality. The evaluation of the foetus has been transformed by the use of ultrasound. Doppler-measured hemodynamic parameters can be used to evaluate a variety of physiological changes that are taking place but cannot be detected clinically. Doppler ultrasound can detect any signs of utero-placental insufficiency as well as the condition of the fetoplacental vascular bed. According to Doppler ultrasound, there is a risk of an unfavourable pregnancy outcome if there is evidence of utero-placental insufficiency1,2. Fitz Gerald and Drumm’s 1977 demonstration of the Doppler frequency shift waveform from the umbilical arterial circulation marked the beginning of Doppler’s reported application (3,4).</p>
      <p>Doppler enables for the assessment of the fetus’s response to stress since it is based on the hemodynamics of the blood circulation in the developing foetus. Doppler velocimetry assists in determining the prenatal course and time of birth while monitoring the foetus’ health throughout pregnancy. Before there are any overt signs of foetal distress, doppler alterations are recognised as aberrant blood flow patterns. Doppler is thought to be the most crucial technique for foetal surveillance in IUGR pregnancies and helps to reduce the risk of a poor postnatal outcome by enabling a better study of hemodynamic changes6. METHODS AND MATERIALS This research was done in the Department of Obstetrics and Gynecology at a tertiary care hospital in Karnataka over the course of a year.</p>
      <p>Criteria for Study Group Inclusion Date of last menstrual cycle known Clinical disparity between the dates and fundal height of at least four weeks Based on femur length (FL), biparietal diameter (BPD), and belly circumference, USG indicates foetal weight less than the 10th percentile of gestational age (AC). Criteria for the Control Group’s Inclusion Normal expecting mothers who are aware of the date of their last period clinical evaluation and USG Exclusion Standards • persistent hypertension • Diabetes and cardiovascular disorders • hypertension caused by pregnancy • a poor history of pregnancy Hydramnio a number of pregnancies Registration and Approval ethics committee approval was acquired from the hospital ethical committee prior to enrollment.</p>
      <p>IEC-KMC MLR 12-14/289</p>
      <p>Methodology All of the registered subjects provided their informed consent. The study group consisted of cases with foetal growth restriction diagnoses. As controls, healthy pregnant women were used. A thorough history and examination were conducted. The Philips HD7XC with 5 MHz was used to perform ultrasound. To validate gestational age, foetal biometry was performed. A clear waveform was acquired, a free loop of cord could be seen, and Doppler indices could be calculated. S/D ratio, umbilical artery PI, and middle cerebral artery PI were measured three times, with the average of the results being computed. Each waveform index for that specific gestational age was analysed using the mean and 95% confidence interval.</p>
      <p>“Cerebro-umbilical ratio was computed as the middle cerebral artery pulsatility index to that of the umbilical artery pulsatility index.” Controls and cases were monitored all the way to delivery. As outcome measures, birth weight, apgar score, mode of delivery, and NICU admissions were examined. The outcomes in both groups were compared when the CU ratio was divided into two categories: 1 and &gt;1. Doppler parameter significance was established. Conclusion It was discovered that the study group had a higher rate of induced labour, emergency LSCS, apgar scores below 7/10 at 1 minute, and NICU hospitalisation when compared to the control group.Cerebro-umbilical ratio failed to predict the unfavourable outcomes statistically significantly.In growth-restricted pregnancies, umbilical artery S/D ratio was revealed to be a stronger indicator of a poor outcome.</p>
      <p>REFERENCES</p>
      <p>1. Callen. Ultrasonography in Obstetrics and Gynecology,3rd Edition.503-515.</p>
      <p>2. Michael Y.Divon et al; Umbilical Artery Doppler Velocimetry: Clinical utility in high risk pregnancy. American Journal Of Obstetrics and Gynecology, Jan 1996,174:10-14,174:336.</p>
      <p>3. American college of obstetricians and gynecologists. Intrauterine growth restriction; ACOG practice bulletein n0.12.Washington,DC:ACOG;2000.</p>
      <p>4. NHL Journal of Medical Sciences/Jan 2015/Vol 4 issue 1.</p>
      <p>5. Fitzgerald, P.E. Drumm. Non-invasive measurements of foetal circulation using USG, a new method. British Journal Of Medicine 1977;2:1450.</p>
      <p>6. Stuart, Fitzgerald and Drumm. Foetal blood velocity waveforms in pregnancy. British Journal of obstetrics and Gynaec 1980;87:780.</p>
      <p>7. Fleischer A, Schulman H, Farmakides G, Bracerol,Blattner P, Randolph G; Umbilical artery flow velocity waveforms and intrauterine growth restriction. AM J Obstet Gynecol,1985;151:502-505.</p>
      <p>8. Gadelha-Costa A, Spara-Gadelha P, Filho FM,Gadelha EB. Haemodynamic changes in the fetal arteriesduring the second half of pregnancy assessed by Doppler velocimetry. Eur J Obstet Gynaecol.Reprod Biol.2007 Jun;132(2):148-53.</p>
      <p>9. Alfirevic Z, Stampalija T, Gyte GM. Fetal and umbilical Doppler ultrasound in high risk pregnancies.Cochrane Database Syst Rev 2010:CD007529.</p>
      <p>10. American College of Obstetricians and Gynecologists. Intrauterine growth restriction. AJOG practice bulletin No.12. Washington DC: American College of Obstetricians and Gynecologists;2000.</p>
      <p>11. Royal College of Obstetricians and Gynecologists(R- COG). Green-top guidelines. The investigation and management of the small for gestational age fetus. London, UK: RCOG Press;2002.</p>
      <p>12. Marsal K.Routine use of Doppler ultrasound in perinatal medicine. J. Perinat. Med. 1994;22(6):463-74.</p>
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