Author Login

Correspondence to Author: Negar Jamshidi 

Kimia Andisheh Teb Medical and Molecular Laboratory Research Co,Tehran, Iran

Abstract:

The presence of the microbiota in the human gut is reported to have a significant impact on the health of the individual. Recent studies have shown that the microbial imbalance in the gut may play a role in the development of cardiovascular disease. Therefore, as an approach to preventing and treating cardiovascular disease, several studies have examined the role of gut microbiota alteration with probiotics. The World Health Organization’s definition of probiotics is that they are a type of living microorganism whose effects on the person’s health can be observed in sufficient quantities. Strategies for human dietary intervention with probiotic strains and their impact on cardiovascular risk factors such as hypercholesterolemia, hypertension, obesity and type 2 diabetes are the subject of this review. The accumulation of evidence suggests that probiotics can reduce LDL/HDL cholesterol and enhance blood pressure, inflammatory mediators, blood glucose levels, and body mass index. Therefore, it is possible to develop probiotics as dietary supplements with potential benefits for health of the heart. However, there is not only ambiguity regarding the exact strains and dosages of the probiotics that will bring about positive health effects, but also factors like immunity and genetics of the individual that might influence the efficacy of probiotics. For that reason, further studies should be carried out to determine the mechanisms by which probiotics might have beneficial effects on cardiovascular system and also exclude any possible negative impact on health. The aim of this review is to assess the effects of probiotics on cardiovascular disease.

Citation:

Negar Jamshidi. Probiotic Bacteria: A Promising Approach for Managing CVD Risk Factors. The Journal of Clinical Medicine 2024.