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Journal of Biosciences and Bioengineering, 2025, Volume 8, Issue 1, Pages: 1-9
Molecular Pharming Of Recombinant Proteins In Plants
Correspondence to Author: Sheetal Sinha, Ayan Raichaudhuri*.
1. Amity Institute of Biotechnology, Amity University, Major
Arterial Road (South-East), AA II, New Town, Kolkata 700135,
India.
Abstract:
Plant molecular farming (PMF) refers to modifying the
genetic makeup of plants to obtain transgenic plants which in
turn are utilised to get recombinant proteins. Recombinant
proteins have gained global alertness. Transgenic plants
can be utilised to produce various types of recombinant
therapeutics. Plants are appropriate and acceptable hosts
since the production cost is much less than transgenic
animals, fermentation, or bioreactors. Therapeutic proteins
such as antibodies, cytokines, enzymes, hormones, and edible
vaccines can be produced by incorporating a foreign gene
of a desired nature into a suitable plant. Protein production
is massive as various types of proteins like antibodies and
many others can be produced in molecular farming using
transgenic plants. Commercial materials produced through
molecular farming attract a big market. Molecular farming
opens the opportunity to manufacture affordable modern
medicines for global production. Vaccines produced in this
field prevent many dreadful viral infections. Commercial
sustainability of molecular farming products, proper target
selection, purification, modification in production methods,
and incorporation of advanced technology are needed.
Spectrophotometry and newer techniques like CRISPR/Cas9
have been included in this area of molecular farming. PMF gained much importance during the COVID-19 viral pandemic
producing proteins for diagnostic and preventive purposes
for making vaccines etc. Viral proteins virus-like particles (VLP)
and viral nanoparticles are widely used in recent fields to
produce recombinant proteins.
.
Keywords: Molecular farming, recombinant proteins, non
pharmaceutical recombinant proteins, transient expression
system.
Citation:
Dr.Ayan Raichaudhuri, Molecular Pharming Of Recombinant Proteins In Plants. Journal of Biosciences and Bioengineering 2025.
Journal Info
- Journal Name: Journal of Biosciences and Bioengineering
- Impact Factor: 1.8
- ISSN: 2836-2535
- DOI: 10.52338/Jobb
- Short Name: Jobb
- Acceptance rate: 55%
- Volume: 6 (2024)
- Submission to acceptance: 25 days
- Acceptance to publication: 10 days
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