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Correspondence to Author: Haseem Ashraf, 

Centre for Diagnostic Imaging - Thoracic Section, Akershus University Hospital, Loerenskog, Norway

Introduction: A 75-year-old woman who is healthy, active, and does not smoke was recommended to have a routine chest x-ray due to inadvertent weight reduction over time. Following a chest x-ray (Figure 1) that revealed diffuse consolidation in the right lower lobe, the patient was scheduled for a CT scan of the thorax (Figure 2) within the following month. A 15 × 13 mm ambiguous ground glass opacity lesion was visible on the CT scan of the right lower lobe. The patient was referred for a CT-guided lung biopsy due to the possibility of a malignant outcome (Figure 3). The patient experienced a right-sided pneumothorax during the biopsy, but it resolved with the use of a surgical tube.

Histopathological diagnosis

Lower lobe resection (right) showing a nonmucinous adenocarcinoma in situ.14 mm lesion, centrally situated. Marginaries for free resection. Pathological stage: pTis for AJCC1 and UICC2.

Treatment

The patient underwent a thoracascopic lobectomy of the lower lobe on the right side. After that, the patient had an annual CT thorax scan as a follow-up.

Citation:

Haseem Ashraf. Opacity of Pure Ground Glass: Possible Overdiagnosis?. The Journal of Clinical Oncology 2024.