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Correspondence to Author: Draan M. Niolic, Stojan Lancic. 

Department of Biochemistry and Molecular Biology, Poznań University of Medical Sciences, Poland.

Abstract:

Context: The purpose of this research is to identify the kinds of microbes that affect the development and progression of colorectal cancer (CRC) in people.
Techniques: When the malignancy was surgically removed from individuals with colorectal cancer, three swabs were obtained for microbiological analysis: one from the tumor’s surface, one from the middle of the tumor tissue, and one from the surface of the healthy intestinal mucosa. Findings: Escherichia coli accounted for 70.5% of the microorganisms found in the colon’s healthy mucosa, followed by Enterococcus species (47.7%) and Klebsiella/Enterobacter (20.5%). E. coli was the most common microorganism, accounting for 72.7% of the swabs taken from the tumor tissue’s surface, followed by Enterococcus species. E. Coli accounted for 77.3% of the tumor tissue, followed by Enterococcus species (40.7%), Klebsiella (27%), and Pseudomonas aeruginosa (18.2%). In conclusion, some bacterial species can inhibit the growth of tumor tissue, while others can affect the onset and progression of cancer. Human stool samples examined microbiologically can stop CRC from developing.

Keywords: Escherichia coli, Enterococcus species, Klebsiella, Enterobacter, Streptococcus gordonii, human colorectal cancer, Aeruginosa pseudomonas.

Citation:

Dr.Draan M. Niolic, A Descriptive Cross-Reference Study On The Impact Of Microbes On The Onset And Progression Of Colorectal Cancer In Humans. World Journal Of Biology 2025.