Author Login

Correspondence to Author: Ragata Lóral, klaudia Zywot, Wojciech Ualewski, Adam Jagodzi nski and Narek Murawski. 

Department of Internal Medicine, Yasmed Medical Center Doha, Qatar.

Abstract:

Hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology are the hallmarks of PCOS, a complicated endocrine condition that affects women of reproductive age. Hormonal abnormalities, metabolic dysfunction, and co-occurring mental illnesses, such as eating disorders (EDs), are frequently linked to PCOS. Key hormones, including serotonin, leptin, insulin, ghrelin, kisspeptin, and cortisol, are identified in the review along with their functions in the pathophysiology of PCOS and related mental health issues. Eating and mood issues are linked to serotonin deficit, which is frequently observed in PCOS patients. Variations in the satiety hormone leptin impact the maturation of ovarian follicles and the hypothalamic-pituitary-ovarian axis, raising the risk of infertility.Because of its impact on the limbic system and glucose metabolism, elevated kisspeptin levels in PCOS patients are linked to both hormonal dysregulation and an increased risk of eating disorders like bulimia and binge eating. Insulin resistance and hyperinsulinemia worsen metabolic and reproductive health and encourage eating disorders like bulimia and binge eating. Cortisol and ghrelin also show up as important variables. The analysis highlights the bidirectional association between eating disorders and PCOS, whereby hormonal problems feed a vicious cycle of mental health issues.

Keywords:eating disorders, hormone imbalances, insulin resistance, hyperandrogenism, serotonin, leptin, ghrelin, cortisol, anxiety, depression, and polycystic ovarian syndrome.

Citation:

Dr. Ragata Lóral, Review Of Literature On Polycystic Ovary Syndrome And Eating Disorders. World Journal of Eating Disorders 2025.