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Correspondence to Author: Dad Naln. 

Department of Medical Oncology, Sun Yat-sen University Cancer Center, China

Abstract:

Significant progress has been achieved in the creation of novel cholera vaccines and vaccination prevention techniques. By creating vaccines with greater efficacy and longer duration of protection, particularly in young children and people from non-endemic areas, potential future objectives in this field could build on recent advancements. Additional vibrio antigen discovery could validate protective immune responses as surrogates of protection, a necessity brought on by evidence that the protective mechanism is not the usually seen viriocidal reaction, despite the fact that it parallels evidence of protection.Current obstacles, such as the incidence of cholera epidemics in war-torn countries where short-term vaccination campaigns sometimes prove unfeasible, could be overcome by such additional advancements.This series of articles presents the latest developments in cholera immunology, bioecology, vaccine development, and treatment, which have resulted in aggressive targets for reducing the disease’s incidence and death, which still exists in afflicted areas. The conversation would not be complete without mentioning areas that might be useful for reaching the existing goals but are not prioritized or included in them.

Citation:

Dr.Dad Naln, Reducing Cholera Mortality and Incidence: Unfinished Business. Advances in Vaccines 2025.