Journal of Clinical Obstetrics and Gynecology Research

Popular Keywords

Adrenal Disorders

Breast Cancer and Ovarian Cancer

Endocrine Diseases

Gynecology and Obstetrics

Hormone

Leukoencephalopathy

Trends in Anti-Mullerian Hormone levels among Women attending Fertility Clinic in the UAE.

Correspondence to Author: Muhammad Ahsan Akhtar,

Consultant Gynaecologist, Reproductive Medicine, RCOG accredited sub specialist in Reproductive Medicine, Fakih IVF Fertility Centre Abu Dhabi, United Arab Emirates.

Abstract:

Background Anti-Müllerian hormone (AMH) is widely recognised as the gold standard for assessing ovarian reserve. It is also utilised to predict ovarian response during controlled ovarian stimulation in assisted reproductive technology (ART) and is key indicator of oocyte yield, embryo quality, embryo euploidy, and live birth rates.
Methods This multicentre retrospective study analysed the prevalence of AMH levels in women aged 18–50 years who attended Fakih IVF Fertility Centres (Abu Dhabi, Al Ain, and Dubai) in the UAE for their initial fertility consultation between 2017 and 2023. AMH levels were classified as normal (≥1.3 ng/mL) or low (1.3 ng/mL).
Results: A total of 8,533 women underwent AMH testing, with 63.62% having normal AMH levels and 36.38% showing low AMH levels. No significant differences in AMH levels were observed across demographic groups. From 2017 to 2021, normal AMH levels remained stable at around 63-65%, but in 2022-2023, they declined to 58-59%, indicating a 5-7% increase in the number of patients with low AMH. This rise was particularly notable, with a 4.3-8.3% increase in women under 30 and a 7.7-9.5% increase in those aged 31-40.
Conclusion This study reveals a decline in AMH levels across all age groups during 2022-2023 compared to the previous five years, with a more significant decrease noted in women under 40. Given AMH’s role as a key predictor of successful ART outcomes, early intervention for women under 40 years particularly those under 35, may be crucial for improving ART success. Further research with a larger sample size is necessary to confirm these findings.

Citation:

Muhammad Ahsan Akhtar .Trends in Anti-Mullerian Hormone levels among Women attending Fertility Clinic in the UAE. Journal of Clinical Obstetrics and Gynecology Research 2024.