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The American Journal of Public Health, 2024, Volume 7, Issue 1, Pages: 1-10

Comparative Analysis of Cardiovascular disease risk prediction Models: A Population-based Assessment of the Efficacy of ACC/AHA, Framingham, and QRISK.

Correspondence to Author:  Vahid Mahdavizadeh1*, Moloud Asadi2*, SusanDarroudi3, Nasrin Talkhi4, Mostafa Mansouri1,Habibillah Esmaily5,6, Majid Ghayour-Mobarhan7,Bahram Shahri2#, Mohsen Mouhebati2,3#

1. Clinical Research Development Unit, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2. Department of Cardiovascular, Mashhad University of Medical Sciences, Mashhad, Iran.
3. Vascular and Endovascular Surgery Research Center, Mashhad University of medical sciences, Mashhad, Iran.
4. Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
5. Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
6. Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
7. International UNESCO center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

DOI: 10.52338/tajoph.2024.4171

Abstract:

Objectives Different models have been developed for the assessment of cardiovascular risks, most of which are based in the western countries. To ensure the applicability of these models in non-Western nations, these models should be studied in such populations. The present study aimed to determine their applicability in a population-based study in Iran.
Methods The population in this study were the 9704 adults aged 35–65 years included in the Mashhad stroke and heart atherosclerotic disorder (MASHAD) study. Mashhad study was a 10-year cohort on a population in Iran. The main outcomes in this study were the predicted and observed 10-year CVD risks for the population; the tools used were the ACC/AHA, Framingham, and the QRISK models.
Results Of the research subjects, 5819 (59.97%) were females with an average age of 46.9 ± 7.7 years, and 3885 (40.03%) were men with an average age of 48.3 ± 8.2 years. 1060 (10.9%) CVD events in total were reported by the research participants, with 514 (13.3%) males and 546 (10.7%) women. The estimated CVD risk at baseline was determined by the ACC/AHA to be 5.19±5.91 and 9.27±8.61 for those with and without a CVD incident, the Framingham to be 3.45±4.67 and 6.55±6.45, and the QRISK to be 9.92±8.59 and 10.33±10.52 %.
Conclusions The performance of the QRISK model was moderately better than the two other models, both in men and women. However, all three models performed underestimation in roughly all risk ranges.

Citation:

Mouhebati M. Comparative Analysis of Cardiovascular disease risk prediction Models: A Population-based Assessment of the Efficacy of ACC/AHA, Framingham, and QRISK. The American Journal of Public Health 2024.

Journal Info

  • Journal Name: The American Journal of Public Health
  • Impact Factor: 1.8
  • ISSN: 3064-6677
  • DOI: 10.52338/tajoph
  • Short Name: TAJOPH
  • Acceptance rate: 55%
  • Volume: 7 (2024)
  • Submission to acceptance: 25 days
  • Acceptance to publication: 10 days
  • Crossref indexed journal
  • Publons indexed journal
  • Pubmed-indexed journal
  • International Scientific Indexing (ISI)-indexed journal
  • Eurasian Scientific Journal Index (ESJI) index journal
  • Semantic Scholar indexed journal
  • Cosmos indexed journal

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