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The American Journal of Public Health, 2024, Volume 7, Issue 1, Pages: 1-10
Comparative Analysis of Cardiovascular disease risk prediction Models: A Population-based Assessment of the Efficacy of ACC/AHA, Framingham, and QRISK.
Correspondence to Author: Vahid Mahdavizadeh1*, Moloud Asadi2*, SusanDarroudi3, Nasrin Talkhi4, Mostafa Mansouri1,Habibillah Esmaily5,6, Majid Ghayour-Mobarhan7,Bahram Shahri2#, Mohsen Mouhebati2,3#,
1. Clinical Research Development Unit, Ghaem Hospital,
Faculty of Medicine, Mashhad University of Medical
Sciences, Mashhad, Iran
2. Department of Cardiovascular, Mashhad University of
Medical Sciences, Mashhad, Iran.
3. Vascular and Endovascular Surgery Research Center,
Mashhad University of medical sciences, Mashhad, Iran.
4. Department of Biostatistics, School of Allied Medical
Sciences, Shahid Beheshti University of Medical Sciences,
Tehran, Iran.
5. Department of Biostatistics, School of Health, Mashhad
University of Medical Sciences, Mashhad, Iran.
6. Social Determinants of Health Research Center,
Mashhad University of Medical Sciences, Mashhad, Iran.
7. International UNESCO center for Health-Related Basic
Sciences and Human Nutrition, Mashhad University of
Medical Sciences, Mashhad, Iran.
DOI: 10.52338/tajoph.2024.4171
Abstract:
Objectives Different models have been developed for the
assessment of cardiovascular risks, most of which are based
in the western countries. To ensure the applicability of these
models in non-Western nations, these models should be
studied in such populations. The present study aimed to
determine their applicability in a population-based study in
Iran.
Methods The population in this study were the 9704 adults
aged 35–65 years included in the Mashhad stroke and heart
atherosclerotic disorder (MASHAD) study. Mashhad study was
a 10-year cohort on a population in Iran. The main outcomes
in this study were the predicted and observed 10-year CVD
risks for the population; the tools used were the ACC/AHA,
Framingham, and the QRISK models.
Results Of the research subjects, 5819 (59.97%) were females
with an average age of 46.9 ± 7.7 years, and 3885 (40.03%)
were men with an average age of 48.3 ± 8.2 years. 1060
(10.9%) CVD events in total were reported by the research
participants, with 514 (13.3%) males and 546 (10.7%) women.
The estimated CVD risk at baseline was determined by the
ACC/AHA to be 5.19±5.91 and 9.27±8.61 for those with and
without a CVD incident, the Framingham to be 3.45±4.67 and
6.55±6.45, and the QRISK to be 9.92±8.59 and 10.33±10.52 %.
Conclusions The performance of the QRISK model was
moderately better than the two other models, both in
men and women. However, all three models performed
underestimation in roughly all risk ranges.
Citation:
Mouhebati M. Comparative Analysis of Cardiovascular disease risk prediction Models: A Population-based Assessment of the Efficacy of ACC/AHA, Framingham, and QRISK. The American Journal of Public Health 2024.
Journal Info
- Journal Name: The American Journal of Public Health
- Impact Factor: 1.8
- ISSN: 3064-6677
- DOI: 10.52338/tajoph
- Short Name: TAJOPH
- Acceptance rate: 55%
- Volume: 7 (2024)
- Submission to acceptance: 25 days
- Acceptance to publication: 10 days
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