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• Research Article
• Open Access
• AnneKarin Bär

Orthognathic surgery (OGS) improves function and attractiveness by realigning the teeth and skeleton. OGS has been demonstrated to enhance quality of life (QoL) in a number of ways and is typically used on patients with severe dentofacial abnormalities that cannot be addressed with orthodontics alone.

• Review Article
• Open Access
• Bryan Lim

Although deep inferior epigastric perforator (DIEP) flap breast reconstruction is becoming more and more common, there is debate about how best to employ closed suction drains (CSD) at the abdominal donor site. Current research on the use of CSD, placement/removal criteria, and complications in DIEP flap operations is summarized in this narrative review. There is also discussion of alternative methods and their consequences for postoperative care. Techniques: In August 2024, a comprehensive search was carried out across many databases to find English-language research on the application of CSD in DIEP flap breast reconstruction. Original research on topics including CSD volume criteria, time, problems, substitutes like progressive tension sutures, and effects on patient outcomes and bathing was required for inclusion. Relevant paper references were manually searched.Although CSD may lessen the formation of seromas or hematomas, early removal (≤3 days) did not result with more problems or a shorter hospital stay.

• Review Article
• Open Access
• Bryan Lim

An important development in post-mastectomy therapy is autologous breast reconstruction using the deep inferior epigastric perforator (DIEP) flap, which provides comparable aesthetic results with lower donor site morbidity.

• Review Article
• Open Access
• Masileva RU

Although systemic anticoagulation and its reversal carry known dangers, they are sometimes considered required. However, systemic hemostasis changes are frequently unnecessary when local therapy can make the necessary alterations, especially in plastic surgery patients. An overview of the clinical uses of topical anticoagulant and procoagulant therapy in cosmetic and reconstructive surgery was the goal of this review. Hemostats are frequently used to stop bleeding, local anticoagulants like heparin can increase flap survival, and local tranexamic acid (TXA) has demonstrated promise in attaining hemostasis under diverse situations, albeit this research is still in its infancy. Drug delivery is the primary obstacle to the development of local treatment.

• Editorial
• Open Access
• Pileto Gentiole

The terms “biomaterials,” “cell-based therapies,” and “adipose-derived mesenchymal stem cells” (AD-MSCs) are frequently used interchangeably when addressing methods to enhance tissue regeneration or fix tissue abnormalities. For these kinds of uses, mesenchymal and follicular stem cells, biotechnologies, blood products like platelet-rich plasma (PRP), and biomaterials including mesh, scaffolds, and hydrogels might be useful.