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Correspondence to Author: Dr. Batool Butt, Dr. Farooq, Dr. Naveed Sarwar, Dr. Mohsin Qayyum, Dr. Mujeeb, Dr. bilal. 

Department of Medicine, Foundation University Islamabad, Islamabad 44000, Pakistan

DOI: 10.52338/joid.2025.4598

Abstract:

Objective:To investigate the clinical and microbiological aspects of CRBSIs in the dialysis population of Pakistan and evaluate their short-term outcomes.
Study Design:Quantitative, cross-sectional study
Methodology: A multistage cluster sampling technique was employed to select a representative sample of dialysis centers from various provinces in Pakistan. Within each selected dialysis center, a systematic random sampling method was used to recruit participants who met the inclusion criteria.A self-administered, structured questionnaire was developed to collect data on participants’ demographic characteristics, comorbidities, catheter-related factors.
Results: : Out of 350 participants included in the trial , 89 patients (25.4%) had experienced at least one episode of CRBSI in the previous six months. Blood cultures were positive in 82.0% of cases, with Gram-positive bacteria being the most commonly isolated pathogens (67.4%). Staphylococcus aureus was the most frequently identified pathogen (28.1%). The mean duration of hospitalization for patients with CRBSI was 14.2 days (SD 5.6). The overall mortality rate among patients with CRBSI was 16.9%. Several factors were found to be significantly associated with the incidence of CRBSI, including a history of previous CRBSI (p < 0.001), catheter-related factors such as duration of catheter use (p = 0.002) and lack of catheter care education (p = 0.017), and comorbidities such as diabetes mellitus (p = 0.002) and cardiovascular disease (p = 0.039).
Conclusion: Especially in poor and medium income countries like Pakistan, our results highlight the need of ongoing efforts to prevent and control CRBSIs in the dialysis population.

Keywords:Catheter related blood stream infection, dialysis,short term outcome.

Citation:

Dr.Batool Butt, Clinical And Microbiological Aspects Of Catheter Related Blood Stream Infection In Dialysis Population And Their Short-Term Outcome. Journal of Infectious Diseases 2025.