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Correspondence to Author: R B Nerli^*, Nishant Setya,Saurabh Uplenchwar,Ashwin Bokare,Rakesh Shetty. 

Department of Urology, JN Medical College, KLE Academy of Higher Education and Research (Deemed-to-be-University), JNMC Campus, Nehru Nagar, Belagavi, Karnataka 590010, India

DOI: 10.52338/aou.2025.4238

Abstract:

Introduction: Urolithiasis is known to affect 20-28% of patients with Autosomal Dominant Polycystic Kidney Disease, of whom 50% are symptomatic and 20% require definite urologic intervention. The management of urolithiasis includes oral dissolution therapy, extracorporeal shock wave lithotripsy and surgical treatment. Percutaneous nephrolithotomy (PCNL) has been reported as a method of stone treatment by several experts. In this study we report us experience with PCNL in patients with autosomal dominant polycystic kidney disease (ADPKD) and the outcome of the same.
Materials & Methods:We retrospectively reviewed the outpatient, inpatient records and imaging of all patients with autosomal dominant polycystic kidney disease undergoing PCNL at our centre.
Results: During the study period, a total of 17 patients with a mean age of 47 ± 5.6 years were diagnosed to have renal calculi with ADPKD and underwent PCNL for the same. The mean serum creatinine was 1.8 ± 0.4 mg% and mean size of stones was 18 ± 4.6 mm. No major intra-operative complications were noted. Stone clearance rate with PCNL alone was 94.1%.
Conclusions: The PCNL in ADPKD is safe and effective but can be associated with postoperative bleeding requiring transfusions. Infection of the cysts may be a cause for fever, and prolonged leak.
Keywords: Percutaneous Nephrolithotomy, Urolithiasis, Autosomal Dominant Polycystic Kidney Disease.

Citation:

Dr.R B Nerli, Percutaneous Nephrolithotomy In Patients With Polycystic Kidneys. Annals of Urology 2025.