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• Research Article
• Open Access
• Thiago Augusto Rochetti Bezerra

Retinoblastoma is the most common malignant intraocular tumor of childhood, with important implications for the child’s survival and quality of life. Historically treated by enucleation and external radiotherapy, the management of the disease has evolved significantly with the advent of chemotherapy, which has become a more conservative and effective alternative.

• Review Article
• Open Access
• Kulshrestha Ritu

Lung cancer has a high prevalence and low survival rate in India due to patients presenting at late-stage. The National Cancer Control programs and Tobacco cessation programs are working to improve their diagnosis and management. However, there are no public health programs for Lung Cancer Screening in India.

• Review Article
• Open Access
• Gaurav Prakash

Circulating cell-free DNA (ccf-DNA) and circulating tumor DNA (ctDNA) provide a minimally invasive method for cancer detection and measurement. However, their diagnostic and prognostic significance in hematological malignancies remains ambiguous. This meta-analysis aims to evaluate the prognostic value of ccf-DNA or ctDNA in patients with diffuse large B-cell lymphoma (DLBCL).

• Review Article
• Open Access
• Zeeshan Abbas

As a mutation and genetics-dependent disease Prostate Cancer (PCa) ranks second among all male malignancies while remaining a dominant cause of male cancer fatalities. The BRCA1 and BRCA2 genes work to repair DNA but mutations in these genes make patients more vulnerable to tough types of PCa. BRCA2 mutations increase PCa risk four times more than other mutations including BRCA1 mutations.

• Review Article
• Open Access
• Danilo Coco MD

The management of pancreatic ductal adenocarcinoma (PDAC), particularly in the head of the pancreas, has evolved with the advent of minimally invasive surgical techniques. Robotic duodenopancreatectomy (RPD) and laparoscopic duodenopancreatectomy (LPD) have emerged as two promising approaches.