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Correspondence to Author: Diwan Shrestha,^1* Utsab Man Shrestha,¹ Manish Roy, ¹ Punyaram Kharbuja, ¹ Nickey Pradhan, ² Navindra Phuyal, ³ Shree Krishna Shilpakar ⁴. 

1.Department of Surgical Oncology, Bhaktapur Cancer Hospital, Bhaktapur, Nepal.
2. Department of Community Medicine, Rapti Academy of Health Sciences, Dang, Nepal.
3. Department of Anatomy, Rapti Academy of Health Sciences, Dang, Nepal.
4. Department of Physiotherapy, Bir Hospital, Nepal.

DOI: 10.52338/tejoc.2026.5752

Abstract:

Background:Breast cancer considered as most common, is a leading cause of cancer related death among women worldwide. Early diagnosis and appropriate surgical management are important to improve patient outcomes. There are two primary surgical approaches for early breast cancer treatment: modified radical mastectomy and breast-conserving surgery. This study was conducted with the objectives of assessing and comparing the efficacy and oncological outcomes of breast-conserving surgery and modified radical mastectomy in patients with breast cancer at a tertiary cancer centre in Nepal.
Methods: A retrospective cross-sectional study was designed including data from patients who underwent breast conserving surgery and modified radical mastectomy at Bhaktapur Cancer Hospital, Nepal, from year 2012 to 2018, with the follow up period of at least 5 years postoperatively.
Results: A total of 200 patients were included in the study, with the mean age of 44.1 ± 10.3 years in breast conserving surgery group and 50.1 ± 12.6 years in modified radical mastectomy group. The operation time (69.65 ± 9.05 vs 115.5 ± 20.81) min, incision length (49.5 ± 7.05 vs 108.6 ± 14.07) mm, intraoperative blood loss (37.5 ± 14.96 vs 45.6 ± 8.44) ml, and complication rate (5% vs 20%) were significantly less in BCS group than in MRM group. Furthermore, significant difference was not observed in the local recurrence rate, distant recurrence rate, disease-free survival, and overall survival at 1 and 5 years postoperatively between the BCS and MRM groups.
Conclusion: BCS is as effective in the treatment of early breast cancer as MRM; however, it offers less operation time, incision length, blood loss, and complication rate than MRM.

Keywords: Breast cancer; breast conserving surgery; modified radical mastectomy..

Citation:

Dr. Diwan Shrestha, Comparative Study Of Breast Conserving Surgery And Modified Radical Mastectomy In Patients With Breast Cancer At A Tertiary Cancer Centre. The European Journal of Cancer 2026.