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Correspondence to Author: P D Gupta¹ and Chetana Rajyaguru². 

1. P D Gupta, Former, Director Grade Scientist, Centre for Cellular and Molecular Biology, Hyderabad, India.
2. Department of Microbiology, MVM Science and Home Science Collage, Rajkot, India.

Abstract:

Efficacy of drugs depends on many factors; the most concerning one is gender-based drug metabolism. The metabolic differences found within a species are believed to be due to variations in age, sex, genetics and diseases. The male and female bodies behave differently when it comes to the manifestations and treatments of various diseases. Therefore, some conditions are more favourable in women than in men, and viceversa for drug metabolism. For decades, drug trials were performed almost exclusively on men. Women were eliminated for drug trails because of every month they undergo menstrual cycle, occasionally become pregnant, during these periods their physiology and endocrinology change.

Keywords: Biological factors, sexual dimorphism, menstrual cycle, pregnancy, hormonal changes, change in composition of microbiota.

Citation:

Dr.P D Gupta ,Factors Influencing Drug Metabolism. The Journal of Bone and Mineral Research 2025.