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Correspondence to Author: Ludek Fiala¹ , Jiri Lenz² , Radek Chvatal³ , Vaclav Vetvicka⁴. 

1. Institute of Sexology, Charles University Prague Psychiatric Clinic , Charles University Pilsen, Czech Republic
2. Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Science Brno, Czech Republic
3. Department of Obstetrics and Gynaecology, Znojmo Hospital, Znojmo, Czech Republic
4. University of Louisville, Department of Pathology, Louisville, KY 40202, USA

DOI: 10.52338/tjocm.2025.5142

Abstract:

Endometriosis is a prevalent disorder of the female reproductive system that frequently demonstrates malignant-like characteristics, including invasive growth and recurrence. Despite extensive investigation, the precise mechanisms underlying its pathogenesis remain incompletely elucidated. Accumulating evidence indicates that dysregulation of the immune system plays a central role in disease development and progression. Alterations in both the number and function of immune cell populations, such as macrophages, T and B lymphocytes, and natural killer (NK) cells, have been consistently documented. These findings have led to the hypothesis that immunotherapy may represent a promising novel strategy for the treatment of endometriosis

Keywords: Endometriosis; macrophages; immunity; NK cells; autoimmunity.

Citation:

Dr. Vaclav Vetvicka, Immunity And Endometriosis: A Short Review. The Journal of Clinical Medicine 2025.