Author Login

Correspondence to Author: *J. Leonardo Mayorga Garibaldi¹ , Candido Contreras Méndez ² , Sandra Kira Niño Oberto ² , Nancy Esbeydi Hernández Ávila ³ , Fernando Aguilar Barradas ³ , Mariana Lizett Zárate Torres ⁴ , Jorge Arturo Mayorga Rodríguez ⁵ , Claudia Lizeth Cueto Aragón ⁶ , Jaime Palomares Marín ⁷ , Yaxsier de Armas Rodríguez ^7,8. 

1 Diagnostic and Research Unit in Medical Microbiology and Infectious Diseases, Mexico.
2 Infectious disease specialist at General Hospital, North Zone, Xalapa, Veracruz, Mexico.
3 Internal Medicine Physicians, “Dr. Rafael Lucio” Xalapa, Veracruz.
4 Dermatologist, Private Practice, Mexico.
5 Head of the Research department, Dermatologic Institute of Jalisco, “Dr. José Barba Rubio” Mexico.
6 Children´s Hospital, “Eva Sámano de López Mateos” Morelia, Michoacán, Mexico.
7 University Center of Health Sciences, Department of Microbiology and Pathology, University of Guadalajara, Mexico.
8 Department of Pathology, Hospital Center, Institute of Tropical Medicine, Havana, Cuba.

DOI: 10.52338/aods.2026.5778

Abstract:

Introduction:Nontuberculous Mycobacteria (NTM) constitute a diverse group of bacteria in the genus Mycobacterium. These bacteria are distinguished from M. tuberculosis and M. leprae by their inability to cause tuberculosis or leprosy. Although NTM are generally of low pathogenicity, they have the capacity to cause opportunistic infections, especially in immunocompromised individuals.
Clinical case: We present the case of a male native and resident of Altotonga, Veracruz with a primary immunodeficiency in the IL12 receptor with Mycobacterium abscessus infection diagnosed by PCR, multi-treated without a favorable response
Conclusions: Fistulizing cervical adenitis in an immunocompetent adult that is refractory to antimicrobial and antituberculosis regimens should raise suspicion of resistant MNT.IL-12 deficiency is an autosomal recessive disorder characterized by a predisposition to recurrent and/or severe infections caused by mycobacteria, this mutation was key to the recurrent infections, the poor response to treatment, and the fatal outcome. It is imperative that, in rare and complex cases, we have a multidisciplinary team that addresses each area.

Citation:

J. Leonardo Mayorga Garibaldi, Mycobacterium abscessus Infection In A Patient With Il-12 Receptor Immunodeficiency. Annals of Dermatological Science 2026.