Author Login

Correspondence to Author: Megun A. Czelski, Leadia V. Pallis. 

Biology Department, Bucknell University, Lewisburg, PA 17837, USA.

Abstract:

The renowned cell researcher Sally Hughes Schrader originally used the phrase “pre-metaphase stretch” in 1950 to refer to the elongation of prometaphase chromosomes seen in the early spermatocytes of praying mantids and phasmid insects. Numerous studies conducted since Hughes Schrader’s original discovery have provided explanations for why and how chromosomes may lengthen before metaphase. In this review, we outline Hughes-Schrader’s preliminary research and go over how more recent studies have shed light on and offered a mechanical explanation for this long-standing occurrence.

Keywords:pre-metaphase stretch, prometaphase, bivalent, spindle, meiosis, mitosis, chromosomal architecture, and chromosome condensation..

Citation:

Dr.Megun A. Czelski, Reexamining The Pre-Metaphase Stretch. Journal of DNA Research 2025.