ISSN-registered · Peer-reviewed · Open Access
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Peer-Reviewed · Open Access

The Annals of Internal Medicine

ISSN 3064-6650 Open Access
CROSSREFOPEN ACCESSPEER-REVIEWED
DOICrossref
CC-BYOpen License
OAOpen Access
Peer-Reviewed

Aims & Scope

The Annals of Internal Medicine is a peer-reviewed, open access internal medicine journal published by Directive Publications for clinicians, hospitalists, and clinical researchers in adult and general internal medicine. The journal advances scholarship across the breadth of the discipline and its subspecialties, including cardiometabolic medicine, nephrology, infectious and post-viral disease, geriatric medicine and frailty, and hospital and perioperative care.

We publish original clinical and translational research, narrative and systematic reviews, clinical case reports and case series, and editorials that improve diagnosis, evidence-based management, and patient outcomes. Recent topics span long COVID and the gut-brain axis, frailty assessment in older adults, chronic renal disease, atherosclerosis and vascular inflammation, and postoperative outcomes after surgery.

Every submission undergoes rigorous double-blind peer review. Accepted articles are published open access under a Creative Commons Attribution (CC-BY 4.0) licence with authors retaining copyright, and each receives a permanent Crossref DOI. Content is discoverable through OpenAlex and Google Scholar and is openly harvestable via our OAI-PMH endpoint.

The journal follows COPE ethical principles and serves a global readership of internists, primary care physicians, trainees, and biomedical researchers seeking trustworthy, openly accessible internal medicine research.

Subject Coverage

The Annals of Internal Medicine welcomes original research, reviews, and case reports across the following core areas:

General and Adult Internal Medicine
general internal medicine research · adult medicine clinical studies · primary care internal medicine · diagnostic reasoning in internal medicine · multimorbidity management
Clinical Case Reports and Case Series
internal medicine case report · rare disease case report · paraneoplastic syndrome case report · case series adult medicine · atypical presentation case report
Chronic Disease and Cardiometabolic Medicine
chronic renal disease management · atherosclerosis and cardiovascular risk · metformin chronic kidney disease · cardiometabolic disease research · smoking and vascular inflammation
Infectious and Post-Viral Disease
long covid syndrome research · post viral syndromes · emerging infectious disease review · meningoencephalitis epidemiology · covid 19 neuropathology
Geriatric Medicine and Frailty
frailty syndrome assessment · aging and internal medicine · geriatric clinical research · frailty scale older adults · healthy aging clinical studies
Hospital and Perioperative Medicine
hospital medicine research · postoperative outcomes study · perioperative internal medicine · laparoscopic surgery outcomes · inpatient care quality research

Research Topics

Core subject areas published in The Annals of Internal Medicine — explore related research across our journals.

In Healthy Individuals Neoantigen Central Nervous System Especially to Volkmar Kreisel MD Chemotherapy Cerebellar Ataxia Michael Weber MD Multiple Liver Metastases Autoimmune Response Septic Shock And Jasmin Stadler MD Complete Cure

Articles

Role of presynaptic alfa receptors

Brassai Attila, George Emil Palade University

Infection with COVID-19 and Neuropathological Features

Biofisica Carlos Chagas Filho, Universidade Federal

Frequently Asked Questions

What topics does The Annals of Internal Medicine cover?

The Annals of Internal Medicine covers the full scope of adult and general internal medicine and its subspecialties, including cardiometabolic and renal disease, infectious and post-viral conditions such as long COVID, geriatric medicine and frailty, and hospital and perioperative medicine. It publishes original research, reviews, clinical case reports, and editorials.

Is The Annals of Internal Medicine open access?

Yes. The Annals of Internal Medicine is a fully open access journal. Every accepted article is published under a Creative Commons Attribution (CC-BY 4.0) licence, authors retain copyright, and all content is free to read, download, and reuse with attribution worldwide.

How do I submit a manuscript to The Annals of Internal Medicine?

Authors can submit original research, narrative or systematic reviews, clinical case reports, case series, and editorials through the journal's submission page. Manuscripts should follow standard internal medicine reporting conventions and our author guidelines, and each accepted article is assigned a permanent Crossref DOI.

What article types does The Annals of Internal Medicine accept?

The journal accepts original clinical and translational research, retrospective and observational studies, narrative and systematic reviews, mini reviews, clinical case reports and case series, and editorials relevant to internal medicine and its subspecialties.

How does peer review work at The Annals of Internal Medicine?

All submissions undergo double-blind peer review, in which author and reviewer identities are kept confidential. Manuscripts are assessed for clinical relevance, methodological rigour, and ethical compliance in line with COPE principles before an editorial decision is made.

Is there an article-processing charge, and are waivers available?

As an open access internal medicine journal, The Annals of Internal Medicine applies an article-processing charge on acceptance to sustain open publishing. Waivers and discounts are available; authors who need financial support should contact the editorial office before or during submission.

Who should read and publish in The Annals of Internal Medicine?

The journal serves internists, hospitalists, primary care physicians, residents and fellows, and biomedical researchers. It is ideal for authors reporting clinical studies, diagnostic and management insights, or instructive case reports in adult and general internal medicine who want open, citable, globally discoverable publication.

Will my article be discoverable and citable after publication?

Yes. Each article receives a permanent Crossref DOI for stable citation and is indexed in OpenAlex and Google Scholar, with metadata openly harvestable through the journal's OAI-PMH endpoint. The journal is also preparing applications for additional scholarly indexes.

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