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Correspondence to Author: A. Ba/Ky¹ , I. Tondé² , S. Zalla³ , A. Dienderé¹ , I. Traore¹ , E. Kama³ , S. Diallo¹ , I. Ouedraogo¹ , I. Sanou⁴. 

1. Bogodogo University Hospital Center,
2. Charles De Gaulle University Hospital of Pediatrics,
3. Ouagadougou Regional Blood Transfusion Center,
4. Tengadogo University Hospital Center

DOI: 10.52338/tjocmb.2025.5109

Abstract:

Introduction: Regular and ongoing screening of blood donors for transfusion-transmissible infectious agents is essential to ensure transfusion safety. The objective was to study the infectious markers sought in blood donations at the Banfora Regional Teaching Hospital Blood Bank
Patients and methods: This was a cross-sectional descriptive study on the search for infectious markers such as Agp24/anti-HIV1/2 Ab, HBsAg, anti-HCV Ab and anti-Treponema pallidum Ab in the serum of donors at the blood bank of the Banfora Regional Teaching Hospital from January 1, 2021 to December 31, 2023. The donors’ blood samples were analyzed using Rapid Diagnostic Tests (RDT) according to the national screening algorithm in force for the search for the four infectious markers during the study period.
Results:A total of 10,443 blood donations were recorded and analyzed for markers. All donors (100%) were volunteers, mostly young (94.27%). Males were the majority, with 73.58%. The overall seroprevalence of infectious markers was 14.80%. The average specific seroprevalence over three years was 1.65% (Ag p24/anti-HIV Ab); 8.70% (HBsAg); 2.14% (anti-HCV Ab); and 2.31% (anti-T. pallidum Ab). The prevalence of HBsAg and anti-T. pallidum Ab coinfection was 0.33%.
Conclusion: Serosurveillance of infections transmitted by blood transfusion in donors must be strengthened and the national transfusion policy must focus on voluntary and regular blood donation and the use of automated and efficient tests.

Keywords: blood donation, infectious markers.

Citation:

Dr. A. Ba/Ky,A Study Of Infectious Markers Of Human Immunodeficiency Virus, Hepatitis B Virus, Hepatitis C Virus And Treponema Pallidum In Blood Donations At The Blood Bank Of The Banfora Regional Universitry Teaching Hospital (Burkina Faso). The Journal of Clinical Microbiology 2025.