ISSN-registered · Peer-reviewed · Open Access
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Peer-Reviewed · Open Access

Journal of Toxicological Research

ISSN 2996-1823 Open Access
CROSSREFOPEN ACCESSPEER-REVIEWED
DOICrossref
CC-BYOpen License
OAOpen Access
Peer-Reviewed

Aims & Scope

The Journal of Toxicological Research (JTR) is a peer-reviewed, open access toxicology research journal published by Directive Publications. It advances the science of how chemical, physical, and biological agents harm living systems, spanning organ and systemic toxicology (hepatotoxicity, nephrotoxicity, reproductive and developmental toxicity), environmental toxicology and ecotoxicology, regulatory and pharmaceutical toxicology, and the quantitative methods that underpin them.

The journal welcomes original research, reviews, case reports, and methodological studies on dose-response and benchmark-dose modeling, permitted daily exposure and residual-solvent limits, occupational exposure limit derivation, cleaning-validation and shared-facility risk, in vitro and in vivo testing, heavy-metal and pesticide contamination, and natural-product or antioxidant protection against toxic injury. Work integrating histopathology, biomarkers, dosimetry, and Bayesian or Monte Carlo analysis is especially encouraged.

JTR serves toxicologists, pharmacologists, environmental and occupational health scientists, regulatory and risk-assessment professionals, and graduate researchers. Every accepted manuscript undergoes double-blind peer review.

All articles are published open access under a Creative Commons Attribution (CC-BY 4.0) license with authors retaining copyright, receive a permanent Crossref DOI, and are made discoverable through OpenAlex, Google Scholar, and an OAI-PMH endpoint, in line with COPE ethical principles.

Subject Coverage

Journal of Toxicological Research welcomes original research, reviews, and case reports across the following core areas:

Organ and Systemic Toxicology
hepatotoxicity research · nephrotoxicity biomarkers · drug-induced liver injury study · reproductive toxicity in rats · systemic inflammation toxicity · histopathology toxicology
Environmental and Ecotoxicology
heavy metal contamination risk · pesticide toxicity ecotoxicology · cypermethrin chlorpyrifos toxicity · environmental monitoring biological risk · aquatic toxicology earthworm · fluoride poisoning study
Regulatory and Pharmaceutical Toxicology
permitted daily exposure residual solvent · occupational exposure limit derivation · cleaning validation toxicology · shared manufacturing facility risk · cross contamination limits · regulatory toxicology assessment
Toxicology Methods and Dose-Response
dose-response modeling toxicology · benchmark dose estimation · bayesian experimental design toxicology · markov chain monte carlo dose metric · in vitro inhalation toxicity testing · dosimetry nano aerosols
Natural Products and Antioxidant Toxicology
hepatoprotective natural product study · silymarin antioxidant toxicity · tanacetum parthenium hepatoprotection · plant extract reproductive toxicity · reactive oxygen species paracetamol · antioxidant protection against toxicity
Clinical and Forensic Toxicology
substance abuse prevalence study · drug treatment center research · venom toxicology stonefish · clinical toxicology case report · poisoning case study · tobacco transfer toxicology

Research Topics

Core subject areas published in Journal of Toxicological Research — explore related research across our journals.

Residual Solvant Tolerable region liver toxicity Tanacetum parthenium Cleaning Validation Markov ChainMonteCarlo Reactive oxygen species Paracetamol Multipurpose/Shared Manufacturing Facility Toxicology data analysis. Silymarin. Cross Contamination. Heavy Metals

Articles

FINDING SIMULTANEOUS TOLERABLE DOSAGE COMBINATIONS FOR MULTIPLE OUTCOMES AND MULTIPLE STRESSORS

Statistical Sciences, Operations Research, Virginia Commonwealth University

Frequently Asked Questions

What topics does the Journal of Toxicological Research cover?

JTR covers the breadth of toxicology research: hepatotoxicity, nephrotoxicity and reproductive toxicity; environmental toxicology and ecotoxicology including heavy metals and pesticides; regulatory and pharmaceutical toxicology such as permitted daily exposure, residual solvents, occupational exposure limits and cleaning validation; dose-response and benchmark-dose modeling; and natural-product or antioxidant protection against toxic injury.

Who should publish in or read the Journal of Toxicological Research?

JTR is intended for toxicologists, pharmacologists, environmental and occupational health scientists, regulatory and risk-assessment professionals, and graduate researchers who study how chemical, environmental, and biological agents affect human, animal, and ecological health.

What article types does the Journal of Toxicological Research accept?

The journal accepts original research articles, review and systematic-review articles, case reports, methodological and modeling studies, and editorials across experimental, environmental, regulatory, and clinical toxicology.

Is the Journal of Toxicological Research open access, and who holds copyright?

Yes. Every article is published open access under a Creative Commons Attribution (CC-BY 4.0) license, so the work is free to read and reuse with attribution, and authors retain copyright to their work.

How do I submit a toxicology manuscript to JTR?

Use the journal's submit page and follow the author guidelines for formatting, ethics, and data-availability requirements. All submissions undergo double-blind peer review, and accepted articles receive a permanent Crossref DOI.

Does the Journal of Toxicological Research charge an article-processing fee, and are waivers available?

An article-processing charge applies only on acceptance; there is no submission fee. Waivers and discounts are available on request to support authors with limited funding, including those from lower-income regions.

How is the Journal of Toxicological Research discoverable and indexed?

Articles carry permanent Crossref DOIs and are discoverable through OpenAlex, Google Scholar, and an OAI-PMH endpoint for harvesting. The journal follows COPE ethical principles and is preparing applications for additional scholarly indexes such as DOAJ as it grows.

What makes JTR distinct from other open access toxicology journals?

JTR welcomes work that bridges experimental, environmental, and regulatory toxicology, with particular openness to quantitative dose-response methods (benchmark dose, Bayesian and Monte Carlo approaches) and to applied pharmaceutical-toxicology topics such as permitted daily exposure and cleaning-validation limits that more general journals often overlook.

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